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The Latest on Week 4 in the NFL (all times EDT):6:10 p.m.The San Francisco 49ers are having to do some major reshuffling on the offensive line with both of their tackles out.Left tackle Joe Staley injured his knee […]

SANTA CLARA, Calif. (AP) — Another miscommunication almost led to another game-altering interception for Jimmy Garoppolo.Only this time, the San Francisco 49ers got bailed out by a flag and held on to beat the D […]

SANTA CLARA, Calif. (AP) — With Marquise Goodwin being ruled out for Sunday’s game against Detroit, San Francisco 49ers rookie wide receiver Dante Pettis is slated for his first NFL start.Coach Kyle Shanahan m […]

SANTA CLARA, Calif. (AP) — The San Francisco 49ers have plenty of holes to fill before their Week 2 game against the Detroit Lions — starting on the offensive line.Two right guards were lost to injury in Sun […]

SANTA CLARA, Calif. (AP) — Jimmy Garoppolo didn’t feel the need to throw any chairs, yell at teammates or do just about anything different following a season-opening loss.Sure, he might have lost his first game a […]

With all the excitement around the NFL last weekend, it was one high-scoring Saints-Buccaneers game that brought home all the money in daily fantasy contests.Tampa Bay quarterback Ryan Fitzpatrick threw for […]

DETROIT (0-1) at SAN FRANCISCO (0-1)Sunday, 4:05 p.m. ET, FoxOPENING LINE – 49ers by 3 1/2RECORD VS. SPREAD – Detroit 0-1, San Francisco 0-1SERIES RECORD – 49ers lead 37-28-1LAST MEETING – Lions beat 49ers 32-17, […]

SANTA CLARA, Calif. (AP) — Matt Patricia got an early taste of what Jimmy Garoppolo was capable of doing as an NFL quarterback.As soon as Garoppolo was drafted in the second round by New England in 2014, he got t […]